On 9th of February 2006, MERCY Malaysia signed a Memorandum of Understanding (MoU) with Malaysia Airlines (MAS). Datuk Dr. Jemilah Mahmood, President of MERCY Malaysia, signed the MoU on behalf of out organisation, while MAS was represented by its Chairman, Dato' Dr. Munir Majid. The signing ceremony was witnessed by MERCY Malaysia's Executive Committee members and staff members from both organisations and the media.

The signing of the MoU officially marked the beginning on the one year 'Hope for Humanity Campaign' initiated by both organisations. It allowed MERCY Malaysia and MAS to establish a framework for strategic collaboration via a humanitarian assistance programme. The areas of collaboration included complimentary air passage for emergency humanitarian missions, fundraising and promotional activities as well as the training of MAS staff members for relief and humanitarian work.